i live up in the mountains and so am quite accustomed to driving in these conditions, however, my sister is a sales rep and drives everyday still doesn´t have much confidence to drive in this area.
would suggest for your first experience of driving a hire car in tenerife and going upto Teide that you follow the main road to Guia de Isora and continue along that road through Chio. As you leave Chio there is a well signposted turnoff for Teide with a very good road that the buses and tour operators use. The views are stunning and it is possible, weather permiting, to see the three island of La Palma, El Hierro and La Gomera.
Safe driving and happy holidays
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